The Antibacterial Activity of Bajakah Tampala Extracts (Spatholobus littoralis Hassk.) Mouthwash Formulation Inhibited Dental Plaque against Streptococcus mutans
11 Halaman
Penulis
ISSN
2339-0948 (ONLINE)
Penerbit
Universitas Gadjah Mada
Diterbitkan pada
30/08/2024
Bahasa
English
Kata Kunci
Abstrak
Dental plaque is the main cause of dental caries caused by Streptococcus mutans, with a high prevalence in Indonesia. Currently, the mouthwash market contains high levels of alcohol, which can cause long-term side effects. Tampala bajakah root (Spatholobus littoralis) is used in traditional medicine by the Dayak community in Central Kalimantan. Bajakah Tampala root has antibacterial activity produced by flavonoids and phenolic compounds. The development of herbal cosmetics can be achieved through Bajakah Tampala mouthwash formulations to prevent dental plaque caused by Streptococcus mutans infection. In this study, ultrasound-assisted extraction (UBT) and infusion (IBT) were used to derive the active compounds of Bajakah Tampala root extract. Various concentrations of UBT (20–80%) and IBT (10%) were evaluated for antibacterial activity using the disk diffusion method. The results showed that the positive control and 80% UBT had antibacterial activity higher than other extracts, with an inhibition zone of 14.01 ± 2.70 mm. Based on these results, an effective mouthwash dosage formulation can be developed at 80% UBT. The formulation evaluation of the mouthwash assessed viscosity, homogeneity, pH, and organoleptic tests. The UBT mouthwash product has qualified formulation evaluation parameters. This research contributed to the innovation of herbal cosmetics by developing the potential of Indonesian medicinal plants.