FORMULASI SIRUP EKSTRAK DAUN SENDOK (Plantago mayor L.) SEBAGAI EKSPEKTORAN DENGAN PARAMETER UJI MUKOLITIK

8 Halaman

Penulis

ISSN

2502-9444 (ONLINE)

Penerbit

Univeristas Muslim Indonesia, Indonesia

Diterbitkan pada

31/07/2017

Bahasa

Indonesia

Kata Kunci

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Abstrak

Traditional medicines that derive from the plants processed in the form of traditional herb have provided a lot of contribution to the maintenance of the health of the community. Greater plantain (Plantago mayor L.) is one of the natural materials that is useful as an expectorant; however, so far the use is still processed traditionally by the community. To find out and make sure that the ethanol extract of greater plantain (Plantago mayor L.) can be formulated to be syrup expectorant, then to determine the most effective concentration in lowering the viscosity of fluid mucus of every formula made. In this research, the syrup ethanol extract of greater plantain (Plantago mayor L.) was made with concentration variations of 6%, 8%, and 10%. Observation was made by looking at the lowering of viscosity of fluid mucus that has been diluted with phosphate buffer pH 7 by using viscometer Ostwald through the flow time. Based on the test result ANSIRA to 3 formulas of syrup expectorant and negative control, it was proved that the concentration of ethanol extract of greater plantain (Plantago mayor L.) in the treatment of this research significantly affected in lowering the viscosity of mucus with price F count > F table or 66.3181 > 4.07 on the test level of 5% and 66.3181 > 7.59 on the test level of 1%. With the price KK 4.11% then further test was done using BNJ test. Based on the test result BNJ, it was known that the formula of syrup expectorant that is most effective is the formula II with the concentration of ethanol extract of greater plantain 8%.

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