Kata Kunci

Abstrak

Background: Cholelithiasis, although rare in children, poses significant risks, particularly for those with underlying conditions such as thalassemia. This study aims to describe the manifestations and management of cholelithiasis in children with thalassemia. Case: A 12-year-old girl with beta-thalassemia major presented with recurrent right upper quadrant abdominal pain and vomiting. Imaging studies revealed cholelithiasis and choledocholithiasis. Due to complications associated with her thalassemia, she underwent endoscopic retrograde cholangiopancreatography (ERCP) for gallstone removal, followed by laparoscopic cholecystectomy. Post-operatively, the patient was managed for post-ERCP pancreatitis and bleeding concerns. She recovered well and is scheduled for follow-up. Discussion: In beta-thalassemia, increased bilirubin production, iron overload, and altered bile properties contribute to a heightened risk of cholelithiasis. The patient exhibited typical symptoms of cholelithiasis and successfully underwent laparoscopic cholecystectomy following initial ERCP. Post-ERCP pancreatitis was managed effectively, and the patient made a satisfactory recovery. Conclusion: This case highlights the increased risk of cholelithiasis in children with thalassemia and emphasizes the importance of early diagnosis and timely intervention to achieve optimal outcomes.