Kata Kunci

Abstrak

Introduction: Bullous cellulitis is a rare but distinct form of cellulitis characterized by the rapid development of erythema and bullae. It is primarily caused by beta-hemolytic streptococci but can also be associated with less common pathogens like Coagulase-Negative Staphylococcus (CoNS), particularly Staphylococcus haemolyticus. Individuals who are immunocompromised or have a history of malignancy are at higher risk for such infections. Local complications, including the formation of bullae, are more likely to occur in patients with obesity. Case Presentation: A 48-year-old woman presented with tensed, loose-walled blisters on the right thigh, exhibiting a reddish base. Her medical history included thyroid cancer, acute renal failure, and a pelvic femur mass. Upon examination, the patient was unconscious and on a ventilator. Dermatological evaluation revealed loose bullae with a positive Nikolsky sign, tense bullae over erythematous patches with ill-defined, irregular edges, and warmth upon palpation. Laboratory findings indicated leukocytosis, hypoalbuminemia, and the presence of CoNS bacteria in blood culture. The ALT-70 score was 5. Conclusion: Bullous cellulitis is a rare condition typically observed in patients with immunocompromised states and obesity. Although CoNS is generally a commensal bacterium, it can act as a pathogen in such cases. The prognosis can be poor, with high mortality rates associated with significant complications.