Kata Kunci

Abstrak

The type of scars varies from mild fine-line scars to abnormal scars, and treatment will differ according to their type, location, symptoms, and severity. Scars significantly impact human life physically, aesthetically, psychologically, and socially, making the choice of treatment very important. Treatment for scars can be done conventionally in healthcare facilities or through traditional methods. Chinese traditional medicine is known to have a major impact on scar treatment. Wound healing consists of three initial stages: inflammatory, proliferative, and remodeling. Chicken bile is known to have a low but strong bilirubin level with little biliverdin. These agents can serve as antipyretic, antioxidant, anti-inflammatory, and anti-atherogenic, aiding wound healing. Bile also supports protein metabolism, fat metabolism, energy production, and glycogen synthesis. Most importantly, bile contains matrix metalloproteinases (MMPs) that degrade type IV collagen, which plays a crucial role in the wound reepithelization process. MMPs alter the wound matrix, enable cell migration, and contribute to tissue remodeling. Thus, MMPs are essential in wound healing.